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Gold and silver for Canadian divers at Commonwealth Games

EDINBURGH, Scotland – Meaghan Benfeito of Montreal and Roseline Filion of Laval won the gold medal Wednesday on women’s 10-metre synchro while Jennifer Abel of Laval and Pamela Ware of Beloeil, Que., took silver on three-metre synchro at the Commonwealth Games.

Pamela Ware wins first Canadian diving title

Pamela Ware wins first Canadian diving title
Pamela Ware wins first Canadian diving title

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Genomics of pain in osteoarthritis.

Genomics of pain in osteoarthritis.

Thakur M, Dawes JM, McMahon SB.

Source

Neurorestoration Group, Wolfson CARD, School of Biomedical Sciences, Kings College London Guy's Campus, London SE1 1UL, UK. Electronic address: thakurmatthew@gmail.com.

Abstract

Osteoarthritis (OA) accounts for the majority of the disease burden for musculoskeletal disorders and is one of the leading causes of disability worldwide. This disability is the result not of the cartilage loss that defines OA radio graphically, but of the chronic pain whose presence defines symptomatic OA. It is becoming clear that many genes, each with a small effect size, contribute to the risk of developing OA. However, the genetics of OA pain are only just starting to be explored. This review will describe the first genes to have been identified in genomic studies of OA pain, as well as the possible dual roles of genes previously identified in genomic studies of OA in the context of pain. Difficulties associated with attempting to characterize the genetics of OA pain will be discussed and promising future avenues of research into genetic and epigenetic factors affecting OA pain described.

Copyright © 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

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